Mr. Thomas Gicquel | Drug Metabolism | Best Researcher Award
CHU Rennes | France
Mr. Thomas Gicquel is an accomplished associate professor in pharmacology and a biologist specializing in biological and forensic toxicology at the Faculty of Pharmacy and University Hospital in Rennes, France. With a strong academic foundation in pharmaceutical sciences, biology, pharmacology, and addictology, he has combined clinical expertise with research excellence throughout his career. His professional journey includes significant roles as a pharmacist in hospital pharmacy, cellular biology, and toxicology laboratories, where he contributed to pharmaceutical control, drug management, cancer research, assay development, and clinical studies. He has been deeply involved in teaching pharmacology at the Master and Pharmacy levels, delivering extensive academic instruction while mentoring numerous students, including doctoral candidates. His commitment to advancing toxicological sciences is evident through his innovative research, notably in the metabolism of emerging drugs and the application of molecular networking approaches for toxicological analysis. He has contributed extensively to scientific literature with a substantial number of publications, invited conferences, oral communications, and poster presentations, establishing himself as a respected voice in his field. His research has provided valuable insights into the metabolism of psychoactive substances, synthetic drugs, and toxic compounds, supporting both clinical and forensic applications. Beyond publications, his innovation is marked by a patent related to a novel method to treat hepatotoxicity induced by amanitins, demonstrating his dedication to translational research with clinical impact. His academic influence is further reflected in his impressive record of citations, with 1,798 citations across 1,534 documents, 92 scientific papers, and an h-index of 23. Through his teaching, mentorship, and multidisciplinary collaborations, Mr. Thomas Gicquel has fostered the growth of future scientists and advanced the understanding of toxicology, pharmacology, and public health.
Featured Publications
Allard, S., Allard, P. M., Morel, I., & Gicquel, T. (2019). Application of a molecular networking approach for clinical and forensic toxicology exemplified in three cases involving 3-MeO-PCP, doxylamine, and chlormequat. Drug Testing and Analysis, 11(5), 669–677.
Le Daré, B., Ferron, P. J., Allard, S., Allard, P. M., Clément, B., Morel, I., & Gicquel, T. (2020). New insights into drug metabolism of quetiapine using molecular networking. Scientific Reports, 10(1), 19921.
Gicquel, T., Pelletier, R., Richeval, C., Gish, A., Hakim, F., Ferron, P. J., Mesli, V., Allorge, D., Morel, I., & Gaulier, J. M. (2022). Metabolite elucidation of 2-fluoro-deschloroketamine (2F-DCK) using molecular networking across three complementary in vitro and in vivo models. Drug Testing and Analysis, 14(1), 144–153.
Pelletier, R., Le Daré, B., Ferron, P. J., Le Bouëdec, D., Kernalléguen, A., Morel, I., & Gicquel, T. (2023). Use of innovative, cross-disciplinary in vitro, in silico and in vivo approaches to characterize the metabolism of chloro-alphapyrrolidinovalerophenone (4-Cl-PVP). Archives of Toxicology, 97(3), 671–683.
Pelletier, R., Le Daré, B., Le Bouëdec, D., Bourdais, A., Ferron, P. J., Morel, I., Porée, F. H., & Gicquel, T. (2024). Identification, synthesis and quantification of eutylone consumption markers in a chemsex context. Archives of Toxicology, 98(1), 151–158.