Yalong Wang | Epigenetics | Best Researcher Award

Mr. Yalong Wang | Epigenetics | Best Researcher Award

Mr. Yalong Wang | The University of Texas MD Anderson Cancer Center | United States

Mr. Yalong Wang is an Instructor in the Department of Epigenetics and Molecular Carcinogenesis at The University of Texas MD Anderson Cancer Center. His scientific journey reflects strong expertise across animal science, cell biology, immunology, and epigenetics. He has contributed significantly to understanding molecular mechanisms in cancer biology, host-pathogen interactions, and protein arginine methylation. His innovative research includes developing pan-methylarginine antibodies, creating SND1 mouse models, and discovering novel methylation reader domains. With prior experience in both academia and biotechnology industries, Mr. Yalong Wang combines leadership and collaborative skills with scientific excellence, driving forward discoveries with clinical and therapeutic implications.

Professional Profile

Scopus

Orcid

Education

Mr. Yalong Wang his academic career with a Bachelor’s degree in Animal Science from Shanghai Jiaotong University. He then pursued a doctoral degree in Cell Biology at the University of Chinese Academy of Sciences, where his research uncovered the role of NLRC5 in antigen presentation. Building on this foundation, he continued postdoctoral training in Immunology at the University of Science and Technology of China. His second postdoctoral fellowship was completed at UT MD Anderson Cancer Center, where he specialized in epigenetics and molecular carcinogenesis. This strong and diverse educational background prepared him to bridge fundamental science with translational insights.

Experience

Dr. Wang has a distinguished record in both academia and industry. He began his career as an antibody engineer and project leader in biotechnology companies, where he contributed to therapeutic antibody development. His academic path continued with postdoctoral research in immunology in China, followed by advanced training in epigenetics at MD Anderson Cancer Center. He developed innovative antibody tools, engineered mouse models, and collaborated on drug discovery studies. Currently serving as an Instructor at MD Anderson, he leads projects on methylation readers and cancer regulation. His experience integrates discovery research, translational application, and mentorship of junior scientists.

Research Interests

Dr. Wang’s research centers on epigenetics, immunology, and host-pathogen interactions. He is deeply interested in protein arginine methylation, with a focus on developing antibody tools and identifying novel methylation readers that regulate transcription, RNA splicing, and cancer signaling pathways. His investigations also extend to microbial sensing in the intestine, exploring how deficiencies in helicases such as DHX15 affect antimicrobial defense. Additionally, his studies examine how proteins like SND1 and SART3 influence tumor progression through methylarginine recognition. These research interests bridge fundamental biology with therapeutic opportunities, offering new approaches for treating cancers and immune-related disorders.

Awards

Dr. Wang has received honors recognizing his academic excellence and research potential at multiple stages of his career. During his doctoral studies in China, he was awarded the National Scholarship Excellence Award for outstanding research contributions, along with scholarships from Shanghai Jiao Tong University. More recently, he was recognized internationally with the EMC Travel Award from MD Anderson Cancer Center, acknowledging his impact in the field of epigenetics and molecular carcinogenesis. These honors highlight his consistent ability to produce meaningful scientific advances and his growing reputation as an emerging leader in biomedical research.

Top Noted Publications

Title: NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens
Year: 2012
Cited by: 968

Title: The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells
Year: 2021
Cited by: 145

Title: Pan-methylarginine antibody generation using PEG linked GAR motifs as antigens
Year: 2022
Cited by: 32

Title: A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II
Year: 2022
Cited by: 83

Title: Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma
Year: 2023
Cited by: 21

Title: SART3 reads methylarginine-marked glycine- and arginine-rich motifs
Year: 2024
Cited by: 5

Conclusion

Mr. Yalong Wang combines innovation, technical mastery, and interdisciplinary breadth that position him strongly for recognition as a candidate for the Research for Best Researcher Award. His discoveries have already shaped immunology, cancer epigenetics, and molecular biology, and his trajectory suggests sustained and growing impact in the years to come.

Jialu Huo | Genetic regulation | Best Researcher Award

Mr Jialu Huo | Genetic regulation | Best Researcher Award

Student Researcher, University of California, San Diego, United States  🌟

Jialu Huo is a passionate student researcher at the University of California, San Diego. Since November 2022, Jialu has actively contributed to cutting-edge research in Dr. Saier’s lab, focusing on genetic regulations and transposons. Her dedication to science is evident through her technical expertise, collaborative mindset, and commitment to advancing research methodologies. Alongside managing experimental designs, data analysis, and training new lab members, Jialu has co-authored impactful publications. She aspires to make significant contributions to the scientific community through her unwavering curiosity and analytical acumen.

Profile

Orcid

Education 🎓

Jialu Huo is currently pursuing her undergraduate degree at the University of California, San Diego. Majoring in a specialized field of interest, Jialu has gained profound knowledge of molecular biology and genetics. Her educational journey is complemented by her hands-on experience in advanced research projects and her active role in a well-regarded academic lab. These academic achievements and her practical learning endeavors form the foundation for her future aspirations in research and academia.

Experience 💼

With over a year of research experience in Dr. Saier’s lab, Jialu has worked on two completed projects, one under review, and one ongoing. She has honed her skills in strain development, data collection, and manuscript preparation. Jialu has also mentored lab members on experimental techniques and contributed to critical discussions in research design. Her experiences have strengthened her analytical thinking and technical skills, equipping her to tackle complex challenges in genetic research.

Research Interests 🔬

Jialu’s research interests lie in genetic regulations and transposons, focusing on understanding their mechanisms and implications in bacterial genomes. Her recent work investigates how genomic contexts impact IS5 transposition within the Escherichia coli genome. This curiosity-driven research aims to unravel the molecular intricacies of transposable elements, providing valuable insights into genetic regulation and evolution.

Awards 🏆

Young Scientist Award (Nomination): Recognizing Jialu’s dedication and contributions to genetic research.

Best Researcher Award (Provisional Selection): For the impactful publication, Investigating How Genomic Contexts Impact IS5 Transposition Within the Escherichia coli Genome.

Publications 📚

Investigating How Genomic Contexts Impact IS5 Transposition Within the Escherichia coli Genome

Journal: International Journal of Molecular Sciences

Year: 2024

DOI: 10.3390/ijms25073946

Comprehensive Characterization of fucAO Operon Activation in Escherichia coli

Journal: International Journal of Molecular Sciences

Year: 2024

DOI: 10.3390/ijms25073946

Conclusion

Jialu Huo is a promising candidate for the Best Researcher Award. Her dedication to research, active participation in lab activities, and involvement in the publication process demonstrate her commitment to the scientific community. While there is room for growth in areas such as collaboration and industry involvement, her strong foundation and potential make her a valuable candidate for this prestigious award.